We now know that CP (Chlamydophila pneumoniae) can persist intracellularly in a cryptic and arrested state, that cannot be cultured, is immunologically muted, and becomes resistant to antibiotics.
By 2011, there was 1635 published research on CP as a mechanism of heart disease. Since nothing much can be done to treat CP that lodged inside the wall of the blood vessel the interest and new ideas to treat is not developed. However, chelation therapy has the understood mechanism to bind metal ion.
ECP therapy, A unique opportunity to save countless lives and billions of dollars is being overlooked by the medical community. This technique increases blood flow to the heart, strengthens the circulation, and offers a proven way to treat heart disease in lieu of stents or bypass surgery.
What is this technique? It is called ECP (External Counter Pulsation) FDA approved since 1987 for :
Avert Obesity Crisis, need for aggressive approach
As it relates to longevity, excess body fat robs victims of quality and quantity of life. People who are overweight or obese often have health problems that may increase the risk for heart disease. The obesity can be the cause to myriad other health problems in vicious cycle. They are high blood pressure, high cholesterol, high blood sugar with hyperinsulinism and oestrogen dominant. In addition, excess weight may cause changes to your heart that make it work harder to send blood to all the cells in your body.
The obesity can be the cause to myriad other health problems in vicious cycle. They are high blood pressure, high cholesterol, high blood sugar with hyperinsulinism and oestrogen dominant. In addition, excess weight may cause changes to your heart that make it work harder to send blood to all the cells in your body.
Mercury is biochemical disrupter and an under-recognized epidemic. Mercury, a known neurotoxin, binds to molecules, tissues and cells in the body and sets the stage for serious chronic disease. Main source of toxicity coming from dental filling amalgam although ignore by many dentist including the American Dental Association and the FDA. They downplay the adverse effect of amalgam (51% mercury). The World Health Organization notes that the typical absorbed dose from amalgams is 100 micrograms a day.
Turmeric is chemically diverse in composition. To date, around 235 compounds, primarily phenolic compounds and terpenoids, have been identified from this spice. Of these compounds, 22 are diarylheptanoids and diarylpentanoids, 8 phenylpropene and other phenolic compounds, 68 monoterpenes, 109 sesquiterpenes, 5 diterpenes, 3 triterpenoids, 4 sterols, 2 alkaloids, and 14 other compounds.
In a stress response, the body releasing a burst of cortisol and some other hormones. This “fight or flight” physical reaction is helpful when it comes to surviving an emergency – but when the stress is chronic and unrelenting, the cortisol will be chronically high.
The devastating effects of chronically heightened cortisol is a shorter life, of course preceded by many diseases.
Cigarette smoking is a well-established risk factor in the pathogenesis and progression of IHD, as well as myocardial infarction. 3-13 Smoking increases death from coronary artery disease by 70 percent.3
Furthermore, the excess risk of morbidity and mortality diminishes with cessation of smoking.4-6
Predictably, the benefits of cessation of smoking accrue even in advanced coronary artery disease following percutaneous coronary revascularization.6
Smoking causes norepinephrine and epinephrine release and results in other adrenergically mediated adverse hemodynamic and metabolic events.12
Even passive smoking impairs endothelium-dependent dilatation in healthy young adults.8
Cigarette smoke is a pro-oxidant in pregnant women regardless of antioxidant nutrient intake.9
In human subjects, cigarette smoking raises the pre-smoke nitric oxide-peroxynitrite ratio of 1:0.5 to a post-smoke ration as high 1:9.7
Rat alveolar macrophages challenged by cigarette smoke release nitric oxide and superoxides, which interact with each other to produce peroxynitrite.
Following two to three puffs of smoke, activated phagocytes continue to release nitric oxide and peroxynitrite for up to 30 minutes277 (Deliconstantinos 1994.)
Ethane and pentane are volatile alkanes produced from peroxidation of omega-3 fatty acids, and the breath levels of those compounds are used as indicators of oxidant stress. The breath ethane levels are higher in smokers than in nonsmokers.7 The intake of antioxidants such as vitamin C and E in RDA amounts does not reduce breath ethane levels.
How can the recognized role of tobacco smoking in the pathogenesis of CAD be explained by the hypothesis of AA oxidopathy? Smoking has well-established procoagulant and coronary vasoconstrictive effects.11-13
As discussed earlier, factors directly fan the oxidative coagulative fires within the circulating blood. Cigarette smoke generates an enormous number of free radicals and markedly increases plasma oxidizability.
As indicated earlier, both active and passive smoking impair endothelium-dependent arterial dilatation in healthy adults.8 There is a dose-related inverse relationship between the intensity of passive tobacco smoking and flow-mediated dilatation, indicating direct early arterial damage. Penn et at. reported a dose-dependent size increases of aortic lesions following exposure to 1,2 dimethylbenzene.7
We anticipated and verified by direct microscopic observations, the ability of tobacco smoke to inflict direct plasma and cell membrane injury.
To this purpose, we examined the immediate effects of free radical cascades generated by cigarette smoking on circulating blood in a volunteer who abstained from smoking for a period of 16 hours and then smoked three cigarettes in five minutes.
Blood condition before smoking on the left and after smoking on the right.
Click below for treatment that can help reduce the effect the effect of smoking and also good even you are still smoking.
1. Ali M. Oxidative coagulopaty. In: Syllabus of the Capital University of Integrative Medicine, Washington, D.C., 1997.
2. Ali M. Ascorbic acid reverses abnormal erythrocyte morphology in chronic fatigue syndrome. Am J Clin Pathol. 1990;94:515.273. Weintraub WS, Klein LW, Seelaus PA, et al. Importance of total life consumption of cigarettes as a risk factor for coronary artery disease. Am J Cardiol 1985; 55:660-72.
3. Weintraub WS, Klein LW, Seelaus PA, et al. Importance of total life consumption of cigarettes as a risk factor for coronary artery disease. Am J Cardiol 1985; 55:660-72.27
4. Center for Chronic Disease Prevention and health promotion. Reducing the health consequences of smoking: 25 years of progress: a report of the surgeon general: executive summary.
Importance of total life consumption of cigarettes as a risk factor for coronary artery disease. Am J Cardiol 1985; 55:660-72.274. Center for Chronic Disease Prevention and health promotion. Reducing the health consequences of smoking: 25 years of progress: a report of the surgeon general: executive summary. washington, D.C. Government Printing Office, 1989. (DHHS publication no. (CDC) 89:8411.) (ref for 70% reduction)
4. Waters D, Lesperance J, Gladstone P, et al. Effects of cigarette smoking on the angiographic evolution of coronary atherosclerosis: a canadian Coronary Atherosclerosis Intervention Trial (CCAIT) Substudy. Circulation 1996;94:614-21.
5. Ross R. The pathogenesis of atherosclerosis—an update. N Eng J Med 1986;314:488-500.
6. Hasdai D, Garratt KN, Grill DE, et al. Effect of smoking status on the long-term outcome after successful percutaneous coronary revascularization. N Eng J Med 1997;336:755-61.
7. Penn A, Batastini G, Soloman J, et al. Dose-dependent size increases of aortic lesions following chronic exposure to 7,12 dimethylbenzene. Cancer research. 1981;41:588-92.
8. Celermajor DS, Adams MR, Clarkson P et al. Passive smoking and impaired endothelium-dependent arterial dilatation in health young adults. N Eng J Med. 334:150-54; 1996
9. Schwarz KB, Cox J, Sharma S et al. Cigarette smoking is a pro-oxidant in pregnant women regardless of antioxidant nutrient intake. J Nutr Env Med 1995;5:225-34.
10. Folts JD, Bonebrake FC. The effects of cigarette smoking and nicotine on platelet thrombus formation in stenosed dog coronary arteries: Inhibition with phentolamine. Circulation 1982;65:465-70
11. Grines CL, Topol EJ, O’Niell WW, et al. Effect of cigarette smoking on outcome after thrombolytic therapy for myocardial infacrtion. 1995;91:298-303.
12. Cryer PE, Haymond MW, Santiago JV, Shah SD. Norepinephrine and epinephrine release and adrenergic mediation of smoking-associated hemodyhamic and metabolic events. N Engl J Med 1976;295:573.
13. Goldsmith JR. Carbon monoxide and coronary heart disease. Ann Intern Med 1969;71:199.
There are many newly discovered benefits of the “sunshine vitamin” published on a regular basis these days. There were 33,000 published (and thousands of new publication every year) papers on benefits of vitamin D.
Vitamin D Dose Recommendations
35 units per pound per day
Age 5 – 10
Blood level is so wide and the so called normal is lumpsum of those who very sick in 95% of population. The normal level is not necessary optimum level for health. Furthermore, there is no way to know if the above recommendations are correct. The ONLY way to know is to test your blood. You might need 4-5 times the amount recommended above. Ideally your blood level of 25-OH-D should be 60ng/ml.
What Makes Vitamin D so Special?
First, it’s important to realize that vitamin D is not “just a vitamin,” but rather the only known substrate for a potent, pleiotropic (meaning it produces multiple effects), repair and maintenance steroid hormone that serves multiple gene-regulatory functions in your body.
Each cell in your body has its own DNA library that contains information needed to deal with virtually every kind of stimulus it may encounter, and the master key to enter this library is activated vitamin D.
For example, memory ductile cells in the breast need vitamin D to access DNA that enables the response to estrogen.
So naturally, without sufficient amounts of vitamin D, your cells cannot access their DNA libraries and their functions are thereby impaired.
This is why vitamin D functions in so many different tissues, and affects such a large number of different diseases and health conditions. So far, scientists have found about 3,000 genes that are upregulated by vitamin D.
Receptors that respond to the vitamin have been found in almost every type of human cell, from your brain to your bones. And researchers keep finding health benefits from vitamin D in virtually every area they look.
Vitamin D Deficiency make you unhealthy
Just one example of an important gene that vitamin D up-regulates is your ability to fight infections, including the flu. It produces over 200 anti microbial peptides, the most important of which is cathelicidin, a naturally occurring broad-spectrum antibiotic.
At least five studies show an inverse association between lower respiratory tract infections and 25(OH)D levels. That is, the higher your vitamin D level, the lower your risk of contracting colds, flu, and other respiratory tract infections:
A 2007 studysuggests higher vitamin D status enhances your immunity to microbial infections. They found that subjects with vitamin D deficiency had significantly more days of absence from work due to respiratory infection than did control subjects.
A 2009 studyon vitamin D deficiency in newborns with acute lower respiratory infection (ALRI) confirmed a strong, positive correlation between newborns’ and mother’s vitamin D levels. Over 87 percent of all newborns and over 67 percent of all mothers had vitamin D levels lower than 20 ng/ml, which is a severe deficiency state. (USA data)
Researchers recommend that all mothers’ optimize their vitamin D levels during pregnancy, especially in the winter months, to safeguard their baby’s health.
A 2009 analysis of the Third National Health andNutrition Examination Surveyexamined the association between vitamin D levels and recent upper respiratory tract infection (URTI) in nearly 19,000 subjects over the age of 12.
Recent URTI was reported by:
17 percent of participants with vitamin D levels of 30ng/ml or higher
20 percent of participants with vitamin D levels between 10-30 ng/ml.
24 percent of participants with vitamin D levels below 10ng/ml
The positive correlation between lower vitamin D levels and increased risk of URTI was even stronger inindividuals with asthma and chronic obstructive pulmonary disease.
Another 2009 reportin the journal Pediatric Research stated that infants and children appear more susceptible to viral rather than bacterial infections when deficient in vitamin D. And that, based on the available evidence showing a strong connection between vitamin D, infections, and immune function in children, vitamin D supplementation may be a valuable therapy in pediatric medicine.
Optimizing your vitamin D levels can also help you to prevent as many as 16 different types of cancer including pancreatic, lung, breast, ovarian, prostate, and colon cancers.
But perhaps most important to note is that vitamin D can lower your risk of dying from any cause, according to a new European meta-analysis published in the Archives of Internal Medicinein 2007.
Another group of researchers have calculated that simply increasing levels of vitamin D3 could prevent diseases that claim nearly 1 million lives throughout the world each year, as the widespread vitamin D deficiency seen today is now thought to fuel an astonishingly diverse array of common chronic diseases, such as:
Diabetes 1 and 2
Cold & Flu
Inflammatory Bowel Disease
Signs of aging
Eczema & Psoriasis
Reduced C-section risk
It’s absolutely tragic that dermatologists and sunscreen manufacturers have done such a thorough job of scaring people out of the sun – your optimal source for natural vitamin D. I believe this is one of the major influences that has contributed to the vitamin D epidemic we’re now facing is widespread use of UV blocker.
The journal PLoS One published the results of research on January 24 2014, which indicates that the benefits of omega 3 polyunsaturated fatty acids (PUFAs) to the liver disease.
Researchers at Oregon State University studied the effects of omega 3 in the livers of mice in which nonalcoholic steatohepatitis (NASH) was induced by a standard Western diet consumed for 16 weeks.
Some of the animals received the omega-3 PUFA EPA and/or DHA along with the diet and others received olive oil.
Supplementation with DHA was more effective than EPA at normalizing NASH gene expression markers and other factors altered by the Western diet.
The team found that DHA affected all major metabolic pathways to exert a protective effect against the diet’s ability to induce the disease. The researchers observed changes in vitamin, carbohydrate and lipid metabolism, as well as protein function.
“We were shocked to find so many biological pathways being affected by omega-3 fatty acids,” remarked study coauthor Donald Jump, who is a professor at the Oregon State University College of Public Health and Human Sciences. “Most studies on these nutrients find effects on lipid metabolism and inflammation. Our metabolomics (assess the metabolites) analysis indicates that the effects of omega-3 fatty acids extend beyond that, and include carbohydrate, amino acid and vitamin metabolism.”
“Most studies on these nutrients find effects on lipid metabolism and inflammation. Our metabolomics (assess the metabolites) analysis indicates that the effects of omega-3 fatty acids extend beyond that, and include carbohydrate, amino acid and vitamin metabolism.”
“A lot of work has been done on fatty liver disease, and we are just beginning to explore the potential for DHA in preventing or slowing disease progression,” Dr Jump noted.
“Fish oils, a common supplement used to provide omega-3, are also not prescribed to regulate blood glucose levels in diabetic patients,” he added. “But our studies suggest that DHA may reduce the formation of harmful glucose metabolites linked to diabetic complications.”
Higher omega-3 levels equal less brain shrinkage with age hence maintain better cognitive function
January 22 2014. A report published online on January 22, 2014 in the journal Neurology® reveals an association between higher levels of the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) and greater brain volume in older age.
“These higher levels of fatty acids can be achieved through diet and the use of supplements, and the results suggest that the effect on brain volume is the equivalent of delaying the normal loss of brain cells that comes with aging by one to two years,” commented lead author James V. Pottala, PhD, of the University of South Dakota in Sioux Falls.
The study included 1,111 participants in the Women’s Health Initiative Memory Study, which was a subset study of subjects enrolled in the Women’s Health Initiative. Subjects were between the ages of 65 to 80 years upon enrollment. Blood samples were analyzed for red blood cell fatty acid levels and magnetic resonance imaging was conducted a median of eight years later to evaluate brain volume.
Having a higher blood level of EPA combined with DHA was associated with larger total brain volume and hippocampal volume at the time of the MRI scans. (The hippocampus is an area of the brain involved with learning.) No association with ischemic lesion volumes and omega-3 fatty acids was observed.
“In this cohort of postmenopausal women, lower red blood cell EPA plus DHA levels correlated with smaller total and hippocampal brain volumes, the former being an indication of cognitive aging and the latter being centrally involved with Alzheimer’s disease pathology,” Dr Pottala and his colleagues conclude. “This study thus adds to the growing literature suggesting that higher omega-3 fatty acid tissue levels, which can be achieved by dietary changes, may hold promise for delaying cognitive aging and/or dementia.”
Since widespread screening for prostate-specific antigen (PSA) testing was initiated in the 1990s, mortality rates for prostate cancer have plummeted. That occurred because a rising PSA can serve as an early cancer detection tool and better enables curative treatment.
In 2012, the United States Preventive Services Task Force made a proclamation against PSA screening for most men.
Life Extension® vehemently objected and wrote scathing rebuttals describing the preventable deaths from prostate cancer that would occur if aging men were dissuaded from having annual PSA blood tests.
On April 11, 2017, the United States Preventive Services Task Force released a draft statement that revised their 2012 recommendation against the use of prostate-specific antigen as a screening blood test for prostate cancer. This group now says PSA screening’s benefits outweigh the risks for men between the ages of 55–69 years and point out the option of “watchful waiting” as a factor in changing their position.
While this is a welcome turnaround, it writes off men once they reach age 70 and fails to acknowledge prostate cancer risk in men starting at age 40.
It also uses the term “watchful waiting” which is now obsolete because there is a better option called “active surveillance” whereby a man with a rising PSA can initiate dietary and lifestyle changes to lower his PSA.
As it relates to the “average” man over age 70, the United States Preventive Services Task Force may be correct in as much as the majority of Americans who fail to proactively protect their health are usually in bad shape around age 70. That means they are likely to die of something else before their prostate cancer becomes clinically relevant.
Nevertheless more than 40,000 new prostate cancer diagnose every year and 28,000 died of prostate cancer every year.
PSA screening is thus an essential component of your longevity program because prostate cancer is outrageously prevalent in men as they mature past 55 years.
Altering one’s diet can enable PSA levels to decline and also markedly reduce prostate cancer incidence. PSA blood tests are widely available and we encourage all men over age 40 to have them done annually.
Estrogen dominant in women can cause thirty problems. There can be two ways, normal estrogen but too low progesterone or really too high estrogen. Here we zoom into high estrogen with or without low testosterone in men.
Numerous studies link low testosterone (and excess estradiol) with increased heart attack and stroke risk. Testosterone is intimately involved in the reverse cholesterol transport process, which removes cholesterol from the arterial wall by HDL.
Vitamin C is potent adjunct cancer treatment that can target and kill cancer stem cells, and more.
Cancer is the second leading cause of death and disease worldwide, accounting for almost 9 million deaths in 2015, according to the World Health Organization (WHO).
In the United States, the National Cancer Institute (NCI) estimate that almost 40 percent of U.S. men and women will have developed cancer at one point during their lives.
There are various treatment options available for cancer, like chemotherapy but they are not always effective; most of them are toxic. Furthermore, cancer is immune dysfunction whereas chemotherapy is immune suppression.
Melatonin is sleeping hormone release by pineal gland inside our brain. Melatonin is a potent antioxidant with powerful anti-cancer activity.
Cancer patient commonly prescribed melatonin for few years to help improve immunity to fight cancer. About sixty percent those above 60 year olds are lacking melatonin, worsening by the year.
That explain why elderly people tend to have difficulty to fall asleep and to maintain sleep. Those who maintain ability to have very good sleep live longer live. Melatonin is known for helping some people achieve a better night’s sleep, hence its nickname as “the sleep hormone.”
Lyme disease is a bacterial infection caused by a spirochete—a corkscrew-shaped bacterium called Borrelia burgdorferi. Primarily transmitted by black-legged ticks. These tiny arachnids are typically found in wooded and grassy areas. The Centers for Disease Control and Prevention estimate that 300,000 people are diagnosed with Lyme disease in the US every year. Many experts believe the true number of cases is much higher.
The symptoms are so myriad that many people who actually have Lyme may be misdiagnosed with other conditions.
Size of tick
Since diagnosing Lyme can be difficult, doctors tend to avoid diagnosing or label as Lyme’s disease without definitive evidence by positive blood test, however many quarters believe blood test is not accurate with high false negative.
Inadequate early treatment can turn into chronic disease for many years.
When your family had a heart attack and survive, what is a diet that your doctor will most likely advice? The heart healthy diet otherwise is likely low-fat diet. Is it right?
If low fat diet what do you change for butter, You guessed it – Margarine! Very likely margarine is a substitute.
Margarine is of course, at the top of the list when a low fat diet is prescribed. After all, who would want butter, full of fat and saturated fats at that! At the risk of being incorrect, But margarine …is very dangerous. Margarine is created from vegetable oil and plant base food contain no cholesterol. So the marketing words is “cholesterol free…”
In Malaysia, any symptoms of epigastric either epigastric pain, discomfort or symptoms of reflux and indigestion that leads to discomfort after taking food the word uses by layman are gastric. More often than not their doctors prescribe them antacids or anti-acid or acid reducing medicine under the group Proton Pump Inhibitors (PPI). PPI come with the word – suffix – pyrazole whatever their trade names. The examples of commonly prescribe are omeprazole (Prilosec), lansoprazole, pantoprazole, esomeprazole (Nexium, esomeprazole).
Many of the people especially elderly vulnerable to serious long-term and chronic adverse effect on their cells and organ systems. I have seen so many people are on these medicine for years. Some continue taking for 4 or 5 years prescribe by their doctors. Quite a number complaints of chronic degenerative symptoms due directly to long-term use of these antacids.
Diabetes has become so common that people don’t take it a serious disease anymore. Pre-diabetic can be as many as half of population above 40 years old. A big mistake is downplaying the significant of pre-diabetic, diabetic and the danger of sugar.
The health complications that diabetes fosters are many, including but not limited to the following:
High blood pressure, heart disease, and stroke – 75 percent of diabetics have high blood pressure (130/80 mm Hg or higher). Death from heart disease and risk for stroke is 2 to 4 times higher among people with diabetes.
Higher than optimum level can kill you, reduce to optimum level may save your life
Hemoglobin is inside red blood cell. Each red blood cell contains about 840 millions of hemoglobin, each hemoglobin consists of Iron and protein. Therefore iron is essential for human life because it can bind to oxygen and carry it throughout your tissues, as without proper oxygenation, your cells start dying.
If you have too little iron, you may experience fatigue. This is common in children and premenopausal women. But what many people fail to realize is that too much iron can be equally deadly, and is actually far more common than iron deficiency.
An important study out of Sweden has surprised researchers who found that combining CoQ10 with selenium can dramatically reduce cardiovascular mortality.
This nutrient combination has also been found to improve heart function, improve quality of life, reduce the number of days a patient stays in the hospital, lower cardiovascular mortality risk by 49%, and evenprovide protection years after the subjects stopped taking the supplements.
Since 2004 I have stated that you can easily eat fifteen eggs per week. This is a simple and cost-effective way to add valuable nutrition to your diet, especially high-quality protein, healthy fats and antioxidants — provided you cook them properly that is half or quarter boiled where the yolk is still soft. Meanwhile, not all eggs are the same quality, free roaming chicken is the best. You should be healthier with high quality eggs.
It is not overstatement to say that the best natural food on the planet is eggs. But many of the healthiest foods happen to be rich in cholesterol (and saturated fats), and this isn’t a bad thing. Anything that processed and packed for selling cannot be a good food.
Many people, unfortunately, have been scared away from this healthy food source because they contain cholesterol. Yes, it contains cholesterol but it increase HDL-cholesterol so called “good” cholesterol.
Taking eggs as much as 20 a week do not increase blood cholesterol level and do not increase insulin release. It is a healthy choice of food.
Magnesium is the fourth most abundant mineral in your body. More than 3,750 magnesium-binding sites have been detected on human proteins,1 and it’s required no less than 500 different enzymes in your body.
If you don’t have enough magnesium, your body simply cannot function optimally, and insufficient cellular magnesium levels set the stage for deterioration of metabolic function that can snowball into more serious health problems.
For starters, magnesium is critical for the optimization of your mitochondria, which have enormous potential to influence your health, especially the prevention of cancer.
In fact, optimizing mitochondrial metabolism may be at the core of effective cancer treatment. But your mitochondrial function is also crucial for overall good health, energy, and athletic performance.