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Vitamin D and Cardiovascular Disease

Low Vitamin D associate with heart disease and stroke.

The researchers found that people with higher levels of a pre-hormone (25-hydroxyvitamin D)  had lower blood pressure and were therefore less likely to develop heart disease, stroke and other health problems.

Study on Genetic epidemiology by University College London showed that for every 10% increase in concentrations of 25-hydroxyvitamin D in the blood, there was a 8.1% decrease in the risk of developing high blood pressure.

The researchers say that observational studies have already shown a link between vitamin D and blood pressure, but a large-scale genetic study was necessary in order to prove cause and effect.

“Even with the likely presence of unobserved confounding factors,” says Vimal Karani Santhanakrishnan in a statement, a research associate of the study. “The approach we followed, known as Mendelian randomization, allows us to draw conclusions about causality because the genetic influence on disease is not affected by confounding”

“To put it in simple terms, by using this approach we can determine the cause and effect and be pretty sure that we’ve come to the right conclusion on the subject.”

He adds: “Our study strongly suggests that some cases of cardiovascular disease could be prevented through vitamin D supplements or food fortification.”

However many vitamin D products in the market are very low dose, as low as 250IU. Whereas we require 2,000IU for maintenance. That explain why the vitamin D supplementation shows mix result for osteoporosis. In case of osteoporosis, to start with we need 4,000 – 5,000 IU or even 10,000 for first one or two months before reduce to 4,000IU per day. Now it seems that not only there is benefit for the bone but also good to protect heart disease and stroke.

Vitamin D shortage

Vitamin D deficiency can occur for a number of reasons, particularly for those who follow a strict vegetarian diet, because many of the food sources of vitamin D are in animal-products such as fish oils, eggs, cheese and beef liver. Activation of vitamin into active forms requires sunlight, spending long periods indoors lead to not enough exposure to sun light renders not enough active vitamin D.