GcMAF (Gc Protein-derived Macrophage Activating Factor) occurs naturally in our bodies and instructs macrophages to destroy cancerous cells and foreign invaders by activating them.

Macrophages (Greek: big eaters) are cells originating from monocytes, a type of white blood cell found in the body. Macrophages function in both non-specific defense (innate immunity) as well as help initiate specific defense mechanisms (adaptive immunity) of vertebrate animals.

Their role is to phagocytize (engulf and then digest) cellular debris and pathogens, either as stationary or as mobile cells. They also stimulate lymphocytes and other immune cells to respond to pathogens. They are specialized phagocytic cells that attack foreign substances, infectious microbes and cancer cells through destruction and ingestion.

A macrophage of a mouse stretching its “arms” (pseudopodia) to engulf two particles, possibly pathogens

Where are macrophages found in the body?

Macrophages and other phagocytes are found in the following locations in the body:

Main location Types of phagocytes
Skin * macrophages, resident Langerhans cells, dendritic cells, mast cells
Gut and intestinal Peyer’s patches macrophages
Lungs macrophages, monocytes, mast cells, dendritic cells
Blood neutrophils, monocytes
Bone marrow macrophages, monocytes, sinusoidal cells, lining cells
Connective tissue macrophages, monocytes, dendritic cells, histiocytes
Lymphoid tissue macrophages, monocytes, dendritic cells
Spleen macrophages, monocytes, sinusoidal cells
Thymus macrophages, monocytes

* These locations offer the best sites for GcMAF administration. The skin by subcutaneous (SC) or intramuscular (IM) injection, the gut by oral administration and the lungs by inhalation using a nebulizer.

How does GcMAF work?

GcMAF is a glycoprotein that activates macrophages which in turn increases macrophage activity and transforms them into Natural Killer (NK) cells.

GcMAF has been clinically demonstrated to be largely free of any serious side effects. Only flu-like symptoms in few percentage of those who receive the injection.

What diseases can benefit from GcMAF therapy?

Gc-MAF and/or oral Colostrum MAF macrophage activation therapy is indicated in the treatment of any diseases where there is immune disfunction or where the immune system is compromised, such as cancer, HIV, Hepatitis B, Hepatitis C, Chronic Fatigue Syndrome, Tuberculosis

Commonly, GcMAF is administered by subcutaneous (SC) or intramuscular (IM) injection, 2-3 times per week. GcMAF is usually combination with about 9,000 IU vitamin D3 daily. Effectiveness increase by 2.5 fold with vitamin D3.